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Sambirano is a valley in north west Madagascar producing cocoa beans famous for a particular various brand of premium quality organic and organically produced Malagasy chocolate.

The name also refers to the Sambirano River which originates at flows from ''Massif du Tsaratanana'' and flows into the Ampasindava Bay, where it joins the Ramena river, at south of Ambanja.

<googlemap version="0.9" lat="-13.707701" lon="48.387566" zoom="12" controls="large">-13.710035, 48.387222Sambirano Valley (approximate)</googlemap> The name Sambirano plain is also refers to the plain where the river runs towards the sea, which is highly fertile as it benefits from grounds due to a hot and humid climate, similar to the eastern part of Madgascar, while in general, the west coast of Madagascar is drier.